Conventional cryopreservation techniques use organic solvents such as glycerol and dimethyl sulfoxide to preserve cells in suspension. Nature does things differently, by using specialist macromolecules such as Ice Binding Proteins, Antifreeze Glycoproteins, to control ice growth and mitigate cellular damage at sub zero temperatures.
At the University of Warwick we developed synthetic Macromolecular Cryoprotectants – polymers which dramatically improve cell cryopreservation by mimicking some functions of natural antifreeze proteins. These cryoprotectants protect the cell membrane during freezing. In addition to replacing the majority of solvent based cryoprotectants needed, they can, uniquely, preserve cells in an adherent format.
We are using our macromolecular cryoprotectants to transform how cells are used in research.
Cells can only be stored frozen in suspension, and must be cultured and prepared every time you want to run an experiment.
We have spent the last decade researching macromolecular cryoprotectants - these materials can cryopreserve plated, adhered cells.
Frozen cell products in a thaw and test format. Bankable, and then ready to use when you want. Never culture cells again.
Frozen pre-plated cell models can be banked and stored long term, eliminating batch-to-batch variation and enabling on-demand testing.
Tired of repetitive cell culture and waiting for results?