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Introducing CryoShield: a superior cryopreservation solution

The problem

A new approach

A new approach

Cells can only be stored frozen in suspension, and must be cultured and prepared every time you want to run an experiment.

A new approach

A new approach

A new approach

We have spent the last decade researching macromolecular cryoprotectants - these materials can cryopreserve plated, adhered cells.

Our solution

A new approach

Our solution

Frozen cells in a thaw and test format. No end user cell expansion or culturing required.

CryoLogyx uses a range of proprietary cryoprotectants, developed over several years at the University of Warwick, to achieve unique cryopreservation outcomes and make new frozen products and services. 


Our cryoprotectants are based on large molecules similar to proteins. These are know as Macromolecualr Cryoprotectants, and more closely mimic the structure and function of biomacromolecules used by extremophiles - animals and plants that survive and thrive in extreme enviroments.


This suite of proprietary cryoprotectant materials, which we call CryoShield, enables very high cell recoveries and allows us to cryopreserve cells in non standard formats.


You can find out more about CryoShield by downloading our latested white papers, or by contacting us directly.

Contact us

CryoShield and Blood Far Forward

Casualty Evacuation in Wartime

  • Today, if a solider can be evacuated from the front lines and rapidly transported to a field hospital their chances of surviving the most grievous wounds are high, with just 10% of soldiers succumbing to their wounds in hospital 
  • Nearly a quarter of combat fatalities between 2003-2011 were deemed medically preventable, with 2699 of the 4596 combat deaths occurring in transit to a field hospital. (US DOD)
  •  90% Of those deaths were caused by blood loss  (US AIMR)

The Missing Link in CASEVAC

  • Blood transfusion during transit would improve casualty outcomes, but currently the logistics of always having whole blood (plasma and red blood cells) available at all times, in a format that CASEVAC operators can use, is currently impractical. 

CryoLogyx and Blood Far Forward

  •  At Cryologyx we have developed, and have a global exclusive license to, technology that will enable the washout process to be carried out in minutes, not hours.
  • This will allow blood to be taken from the freezer and made ready in the time a CASEVAC helicopter would take to get to a battlefield casualty.  
  •  Access to blood on demand would reduce combat deaths in the armed forces and provide a world-leading solution to the issue of trauma blood supply 

CryoShield

  • CryoShield has been shown to effectively cryopreserve red blood cell for rapid washout applications, providing healthy viable cells post thaw, with complete cryoprotectant removel in less than 15 minutes from thawing.

Read our paper on red blood cell cryopreservation

Download the Paper

Resources and whitepapers

CryoShield Cryopreserved HepG2 Cell Monolayers Recovery of Viable and Functional Cells (pdf)

Download

CryoShield Cryopreserved HepG2 Monolayer Toxicological Challenge Assays (pdf)

Download

CryoShield Cryopreserved Thaw and Use A549 Cell Models. Recovery and Assay Performance (pdf)

Download

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